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Figure 6 | Molecular Medicine

Figure 6

From: Valsartan Attenuates Atherosclerosis via Upregulating the Th2 Immune Response in Prolonged Angiotensin II-Treated ApoE−/− Mice

Figure 6

The levels of serum cytokines among the three groups and the mRNA expression in the aorta. (A) The levels of serum Th1- and Th17-related cytokines, including IFN-γ, IL-18, IL-17 and IL-23, in the three groups. (B) The levels of serum Th2- and Treg-related cytokines, including IL-4, IL-5, IL-33, IL-10 and TGF-β1, in the three groups. (C) Expression of IFN-γ, TBX21, IL-18, RORγT, IL-17 and IL-23 mRNA in aorta in the three groups. (D) Expression of IL-4, GATA3, IL-5, IL-33, IL-10, TGF-β 1 and FOXP3 mRNA in aorta in the three groups. The values are presented as the mean ± SD; n = 5–7. *p < 0.05 versus group II, **p < 0.01 versus group II, #p > 0.05 versus group II.

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