Figure 1
From: Role of Interleukin-1 in Radiation-Induced Cardiomyopathy
Dose-response effects of XRT. Mice receiving two different doses of radiation in a single treatment (20 or 14 Gy) showed a dose-response effect at echocardiography and with hemodynamic measurements. (A) Contractile reserve assessed at 72 h after receiving XRT treatments (20 or 14 Gy) as a change in left ventricular ejection fraction (LVEF) measured at rest and 3 min after isoproterenol injection. (B) LVEF at rest, measured 4 months after XRT and expressed as percentage reduction versus sham. (C, D) Contractile reserve assessed and LVEDP measured at 4 months after XRT.