Figure 4
From: Role of Interleukin-1 in Radiation-Induced Cardiomyopathy
IL-1 blockade prevents XRT-induced cardiomyopathy. Four months after XRT (14 or 20 Gy), the mice underwent echocardiography to measure LVEF at rest and 3 min after β-adrenergic stimulation (contractile reserve). (A, B) LVEF at rest measured 4 months after XRT (20 or 14 Gy, respectively) expressed as percentage reduction versus sham. (C, D) Contractile reserve measured at 4 months after XRT (20 and 14 Gy, respectively).