Table 1 Cell types of enhancer regions being enriched (P < 0.05) for RA-assoclated SNPs.
From: Enrichment of Genetic Variants for Rheumatoid Arthritis within T-Cell and NK-Cell Enhancer Regions
Cell type | Number of RA-associated SNPs | Number of loci | Cumulative size of enhancers/bp | RA-SNPs/Mb | P |
|---|---|---|---|---|---|
T cell | 33 | 15 | 1,954,612 | 16.88 | 0.0001 |
Natural killer cell | 24 | 10 | 1,609,644 | 14.91 | 0.0004 |
Lymphocyte B lineage | 11 | 6 | 876,029 | 12.56 | 0.008 |
Neutrophil | 13 | 6 | 1,224,325 | 10.62 | 0.013 |
Basophil | 18 | 8 | 2,224,115 | 8.09 | 0.018 |
Dendritic cell | 19 | 10 | 2,457,374 | 7.73 | 0.036 |
Intestinal epithelial | 6 | 2 | 407,986 | 14.71 | 0.039 |
Mast cell | 15 | 8 | 1,792,867 | 8.37 | 0.044 |