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Figure 2 | Molecular Medicine

Figure 2

From: Glucagon-Like Peptide 1 Protects against Hyperglycemic-Induced Endothelial-to-Mesenchymal Transition and Improves Myocardial Dysfunction by Suppressing Poly(ADP-Ribose) Polymerase 1 Activity

Figure 2

GLP-1 suppresses cardiac fibrosis in diabetic mice. n = 6–7 mice for each group. (A) Masson trichrome staining of mouse hearts. (B, C) Quantification of fibrotic areas in the perivascular and interstitial region. Data are mean ± SD. #p < 0.05 versus control, *p < 0.05 versus DM. (D–F) Western blot analysis of collagen I and III expression. Data are mean ± SD. #p < 0.05 versus control, *p < 0.05 versus DM.

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