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Figure 5 | Molecular Medicine

Figure 5

From: Glucagon-Like Peptide 1 Protects against Hyperglycemic-Induced Endothelial-to-Mesenchymal Transition and Improves Myocardial Dysfunction by Suppressing Poly(ADP-Ribose) Polymerase 1 Activity

Figure 5

(A) GLP-1 inhibited HG-induced EndMT by suppressing PARP-1 activation. Immunofluorescence staining of VE-cadherin (red) and α-SMA (green) is shown. Nuclei were counterstained with DAPI (blue). (B, C) VE-cadherin and α-SMA expression were determined by Western blot analysis. Results are from three repeated experiments.

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Molecular Medicine

ISSN: 1528-3658