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Figure 6 | Molecular Medicine

Figure 6

From: Glucagon-Like Peptide 1 Protects against Hyperglycemic-Induced Endothelial-to-Mesenchymal Transition and Improves Myocardial Dysfunction by Suppressing Poly(ADP-Ribose) Polymerase 1 Activity

Figure 6

GLP-1 reduced HG-induced Snail expression by suppressing PARP-1 activation in HAECs. (A-D) PARP-1, PAR and Snail expression were determined by Western blot analysis. (E) Nuclear colocalization of PAR and Snail was analyzed by double immunofluorescence. The red staining represents PAR and the green staining Snail. Results are from three repeated experiments. Data are mean ± SD. #p < 0.05 versus NG, *p < 0.05 versus HG.

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Molecular Medicine

ISSN: 1528-3658