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Table 1 Basic parameters of mice with DM and GLP-1 analog treatment.

From: Glucagon-Like Peptide 1 Protects against Hyperglycemic-Induced Endothelial-to-Mesenchymal Transition and Improves Myocardial Dysfunction by Suppressing Poly(ADP-Ribose) Polymerase 1 Activity

Parameters

Controls (n = 9)

DM (n = 9)

DM+GLP-1 (n =9)

Fasting blood glucose (mmol/L)

56 ± 1.8

16.1 ± 4.5a

15.5 ± 3.5b

Nonfasting blood glucose (mmol/L)

8.3 ± 2.3

25.9 ± 7.7a

24.3 ± 4.6b

Systolic blood pressure (mmHg)

112 ± 5.1

130 ± 9.2a

125 ± 7.4b

Diastolic blood pressure (mmHg)

87 ± 5.2

102 ± 4.6a

99 ± 72b

Body weight (g)

28.7 ± 3.4

21.8 ± 5.1a

22.6 ± 4.5b

Fasting insulin (ng/mL)

0.82 ± 0.19

0.15 ± 0.07a

0.18 ± 0.05b

Nonfasting insulin (ng/mL)

2.11 ± 0.55

0.21 ± 0.15a

0.25 ± 0.12b

  1. Data are means ± SD.
  2. ap < 0.05 compared with controls.
  3. bp < 0.05 compared with DM alone.