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Figure 5 | Molecular Medicine

Figure 5

From: Cannabidiol Protects against Doxorubicin-Induced Cardiomyopathy by Modulating Mitochondrial Function and Biogenesis

Figure 5

CBD attenuates DOX-induced impaired myocardial mitochondrial biogenesis. The effect of DOX and CBD treatment on (A) mitochondrial copy number and expression of (B) PGC1A, (C) PPARA, (D) ERRA, (E,F) UCP2 and UCP3 and (G) MCAD mRNA levels. Pretreatment with CBD improves DOX-induced decreased expression of mitochondrial biogenesis genes. *P < 0.05 versus vehicle group; #P < 0.05 versus DOX group; n = 4–6/group.

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Molecular Medicine

ISSN: 1528-3658