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Figure 2 | Molecular Medicine

Figure 2

From: Pentoxifylline Attenuates Proteinuria in Anti-Thy1 Glomerulonephritis via Downregulation of Nuclear Factor-κB and Smad2/3 Signaling

Figure 2

(A) Quantitative PCR results showing upregulation of glomerular mRNAs for inflammatory cytokines (TNF-α, IL-1 β, MCP-1) and fibrogenic molecules (TGF-β1, TGF-β3, activin-βA) after induction of the nephritis. (B) Representative immunoblotting results showing activation of p-NF-κB p65 and p-Smad2 after induction of the nephritis. Each bar represents the mean ± SEM of three experiments. *p < 0.05; **p < 0.01 versus control at d 0.

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