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Figure 4 | Molecular Medicine

Figure 4

From: Pentoxifylline Attenuates Proteinuria in Anti-Thy1 Glomerulonephritis via Downregulation of Nuclear Factor-κB and Smad2/3 Signaling

Figure 4

(A) IMD-0354 (IMD) attenuated proteinuria on d 1 of the nephritis. (B) SB431542 (SB) attenuated proteinuria on d 3 and 5 of the nephritis. (C) PTX attenuated proteinuria through the course of the nephritis. Each bar represents the mean ± SEM for a group of six rats. *p< 0.05, **p < 0.01 versus control rats; #p < 0.05, ##p < 0.01, versus vehicle-treated nephritic rats. Thy1, vehicle-treated nephritic rats; Thy1 + IMD, nephritic rats treated with IMD-0354; Thy1 + SB, nephritic rats treated with SB431542; Thy1 + PTX, nephritic rats treated with PTX.

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Molecular Medicine

ISSN: 1528-3658