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Figure 2 | Molecular Medicine

Figure 2

From: Angiotensin II Downregulates MicroRNA-145 to Regulate Kruppel-like Factor 4 and Myocardin Expression in Human Coronary Arterial Smooth Muscle Cells under High Glucose Conditions

Figure 2

Effect of angiotensin 2 (Ang II) on miR-145 expression in cultured vascular smooth muscle cells. (A) Exogenous administration of Ang II at 10 nmol/L in usual culture medium without extra glucose treatment for different periods of time. (B) Exogenous administration of different cytokine proteins and valsartan for 4 h. #P < 0.01 versus control. +P < 0.05 versus control. n = 4 per group. (C) Effect of high glucose on secretion of angiotensin II from cultured vascular smooth muscle cells. Ang II was measured by immunosorbent assay. *P < 0.01 versus control. n = 3 per group.

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Molecular Medicine

ISSN: 1528-3658