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Figure 2 | Molecular Medicine

Figure 2

From: Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic Shock

Figure 2

IKK16 protects against multiple organ failure and dysfunction. Rats were subjected to HS and received IKK16 (1 mg/kg; i.v.) or vehicle (Veh) (10% DMSO) at resuscitation. Four hours later, blood was obtained and serum creatinine (A), estimated creatinine clearance (B), serum AST (C), serum ALT (D), amylase (E), lipase (F), CK (G) and lactate (H) were determined. Sham animals were used as control. Data are presented as box and whiskers (minimum to maximum) and the central line represents the median (n = 8−11 animals per group). *p < 0.05 versus sham group and #p < 0.05 versus HS group.

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Molecular Medicine

ISSN: 1528-3658