Figure 4

IKK16 effects on inflammatory cells in kidney and liver. Rats were subjected to HS and received IKK16 (1 mg/kg; i.v.) or vehicle (Veh) (10% DMSO) at resuscitation and 4 h later kidney and liver were obtained. Sham animals were used as control. The representative images for the immunostaining for MPO as a neutrophil marker (A–D, K–N), CD68 as a macrophage marker (F–I, P–S), and the quantitative analysis of the number of cells/mm² (E, J, O, and T) are shown. The scale bar represents 50 µm. Data are presented as box and whiskers (minimum to maximum) and the central line represents the median (n = 5−6 animals per group). *p < 0.05 versus sham group and ^#p < 0.05 versus HS group.