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Figure 7 | Molecular Medicine

Figure 7

From: Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic Shock

Figure 7

IKK16 attenuates serum inflammatory cytokines. Rats were subjected to HS and received IKK16 (1 mg/kg; i.v.) or vehicle (Veh) (10% DMSO) at resuscitation and 4 h later serum concentrations of TNF-α (A), IL-6 (B) and IL-10 (C) were determined. Sham animals were used as control. Data are presented as box and whiskers (minimum to maximum) and the central line represents the median (n = 7−9 animals per group). *p < 0.05 versus sham group and #p < 0.05 versus HS group; n.d.: not determined.

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