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Table 1 Effect of hemorrhagic shock and IKK16 treatment on white blood cells.a

From: Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic Shock

 

Sham + Vehicle

Sham + IKK16

HS + Vehicle

HS + IKK16

WBC (k/µL)

5.34 ± 0.11

5.10 ± 1.38

7.34 ± 1.55

8.17 ± 1.94

Neutrophils (k/µL)

2.11 ± 1.02

1.86 ± 0.66

1.19 ± 1.26

1.95 ± 2.32

Lymphocytes (k/µL)

2.83 ± 1.02

3.03 ± 1.20

5.58 ± 2.10*b

5.6 ± 1.45*

Monocytes (k/µL)

0.33 ± 0.19

0.28 ± 0.03

0.47 ± 0.21

0.56 ± 0.17

Eosinophils (k/µL)

0.06 ± 0.10

0.02 ± 0.02

0.04 ± 0.06

0.03 ± 0.02

Basophils (k/µL)

0.00 ± 0.00

0.01 ± 0.01

0.06 ± 0.06

0.03 ± 0.04

  1. aRats were subjected to HS and received IKK16 (1 mg/kg; i.v.) or vehicle (10% DMSO) at resuscitation and blood was obtained 4 h later. White blood cells, neutrophils, lymphocytes, monocytes, eosinophils and basophils were evaluated. Data are presented as mean ± S.D. (n = 8−11 animals per group).
  2. b*p < 0.05 versus sham group.
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Molecular Medicine

ISSN: 1528-3658