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Table 2 Effect of hemorrhagic shock and IKK16 treatment on red blood cells and platelet parameters.a

From: Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic Shock

 

Sham + Vehicle

Sham + IKK16

HS + Vehicle

HS + IKK16

RBC (M/µL)

6.29 ± 0.38

6.11 ± 0.56

6.67 ± 0.64

6.61 ± 0.59

HGB (g/L)

13.15 ± 0.59

12.73 ± 0.83

13.89 ± 1.24

13.76 ± 1.38

HCT (%)

40.45 ± 1.64

39.13 ± 3.84

42.88 ± 5.20

42.30 ± 4.45

MCV (fL)

64.43 ± 2.29

64.07 ± 0.64

64.20 ± 3.67

63.98 ± 2.48

MCH (pg)

20.93 ± 0.74

20.90 ± 0.61

20.85 ± 0.81

20.81 ± 0.74

MCHC (g/L)

32.52 ± 0.87

32.60 ± 1.14

32.52 ± 1.16

32.53 ± 0.52

RDW-SD (fL)

32.12 ± 1.51

33.67 ± 1.65

32.68 ± 1.61

32.10 ± 1.64

RDW-CV (%)

16.13 ± 1.09

16.80 ± 1.75

17.45 ± 1.73

16.92 ± 1.29

RET# (k/µL)

462.68 ± 67.6

522.3 ± 147.8

501.7 ± 72.4

479.8 ± 59.4

RET (%)

7.40 ± 1.27

8.49 ± 1.85

7.53 ± 0.90

7.29 ± 0.95

PLT (k/µL)

990.50 ± 177.2

1087.3 ± 49.7

830.9 ± 300.7

954.8 ± 126.6

PDW (fL)

8.38 ± 0.57

8.57 ± 0.47

8.85 ± 0.76

8.60 ± 0.50

MPV (fL)

7.42 ± 0.29

7.43 ± 0.23

7.75 ± 0.52

7.60 ± 0.23

P-LCR (fL)

8.87 ± 1.92

9.03 ± 1.23

11.05 ± 3.24

9.47 ± 1.51

PCT (%)

0.73 ± 0.10

0.80 ± 0.04

0.64 ± 0.22

0.72 ± 0.09

  1. aRats were subjected to HS and received IKK16 (1 mg/kg; i.v.) or vehicle (10% DMSO) at the resuscitation and blood was obtained 4 h later. Data are presented as mean ± S.D. (n = 8−11 animals per group).