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Figure 5 | Molecular Medicine

Figure 5

From: Aloperine Protects Mice against Ischemia-Reperfusion (IR)-Induced Renal Injury by Regulating PI3K/AKT/mTOR Signaling and AP-1 Activity

Figure 5

Analysis of oxidative stress in the kidneys after IR insult. (A) Analysis of ROS accumulation. Left panel: representative images for the detection of DCFH-DA fluorescence in the renal sections. Right panel: quantitative analysis of fluorescence intensity of all mice examined. (B) Analysis of SOD activity in the kidneys. IR insult led to a significant reduction of SOD activity, while aloperine pretreatment almost completely restored SOD activity. (C) Analysis of MDA levels in renal lysates. Panels (A–C) present quantitative analysis as mean ± SEM of six mice analyzed for each group. *, P < 0.05; **, P < 0.01; and P < 0.001.

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Molecular Medicine

ISSN: 1528-3658