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Figure 4 | Molecular Medicine

Figure 4

From: An EG-VEGF-Dependent Decrease in Homeobox Gene NKX3.1 Contributes to Cytotrophoblast Dysfunction: A Possible Mechanism in Human Fetal Growth Restriction

Figure 4

Effect of in vitro differentiation on NKX3.1 mRNA expression in placental cells. (A) Quantification of NKX3.1 mRNA expression levels in primary VCT and EVCT cultures from first-trimester placentae (n = 12). 18S rRNA was used as an internal control. (B) Effects of forskolin (10 µmol/L, 72 h) on NKX3.1 mRNA expression levels in BeWo cells. 18S rRNA was used as an internal control. Results are reported as the mean ± SE mol/L from n = 3 independent experiments. Data were analyzed using the Mann-Whitney U test (significant differences, *p < 0.05).

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