Skip to main content
Figure 3 | Molecular Medicine

Figure 3

From: Hypothesis: Neuroendocrine Mechanisms (Hypothalamus-Growth Hormone-STAT5 Axis) Contribute to Sex Bias in Pulmonary Hypertension

Figure 3

Temporal relationships between the sexually dimorphic spontaneous GH secretory profiles and hepatic PY-STAT5 activity levels (DNA-binding gel-shift assay) in the normal rat (adapted from ref. (43) with permission of The Association for the Study of Internal Secretions and The Endocrine Society). Black arrows point to when the liver tissue was harvested for PY-STAT5 analyses. In males, PY-STAT5 peak heights are higher and interpulse levels very low (left panels). In females, peak height is lower and interpulse levels higher than in males.

Back to article page

Molecular Medicine

ISSN: 1528-3658