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Table 1 IC50 values (inhibition in antagonist mode) for human PPARα, PPARδ and PPARγ.

From: Erratum to: A Selective Novel Peroxisome Proliferator-Activated Receptor (PPAR)-α Antagonist Induces Apoptosis and Inhibits Proliferation of CLL Cells In Vitro and In Vivo

Human PPAR

NXT629

NXT962

 

PPARα

78 nmol/L

>15,000 nmol/L

PPARδ

>30,000 nmol/L

>30,000 nmol/L

PPARγ

>30,000 nmol/L

>30,000 nmol/L

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Molecular Medicine

ISSN: 1528-3658