Table 2 In vivo heart functional parameters by echocardiography at 3- and 14-d endpoints.

EDd (mm)

6.1 ± 0.3

6.2 ± 0.2

5.8 ± 0.2

6.3 ± 0.1

7.7 ± 0.1^a,b

6.7 ± 0.1^a

ESd (mm)

2.6 ± 0.2

3.2 ± 0.1^a,b

2.5 ± 0.1

2.8 ± 0.6

4.4 ± 0.2^a,b

3.1 ± 0.1

EDaw (mm)

1.6 ± 0.03

1.5 ± 0.05

1.6 ± 0.02

1.6 ± 0.04

1.2 ± 0.06

1.5 ± 0.06

EDpw (mm)

1.6 ± 0.02

1.6 ± 0.03

1.6 ± 0.02

1.6 ± 0.02

1.8 ± 0.03

1.7 ± 0.03

sAWT %

69 ± 4

51 ± 3^a,b

68 ± 2

73 ± 3

55 ± 5^a,b

72 ± 2

sPWT %

71 ± 4

65 ± 3

70 ± 3

72 ± 3

71 ± 3

71 ± 2

FS%

57 ± 2

46 ± 1^a,b

57 ± 2

55 ± 1

43 ± 2^a,b

54 ± 1

HR

458 ± 15^b

448 ± 17^b

490 ± 6

435 ± 12

401 ± 13

405 ± 14