Galantamine alters antibody responses in immunized mice. KLH immunized mice were administered galantamine (4 mg/kg) or saline 4 h before death. Splenocytes were extracted, plated at 2 × 105 in 96-well plates and incubated with indicated µg/well KLH. KLH-specific IgG (A) and total IgE (B) was determined by ELISA. Galantamine affected antibody levels (IgG, p < 0.05; IgE, p < 0.01 by two-way ANOVA; *p < 0.05 by Bonferroni posttest).