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Figure 4 | Molecular Medicine

Figure 4

From: Transgenic Expression of miR-222 Disrupts Intestinal Epithelial Regeneration by Targeting Multiple Genes Including Frizzled-7

Figure 4

miR-222 aggravates gut barrier dysfunction in mice exposed to CLP (A) Changes in gut permeability 24 h after CLP Values are mean ± SEM of data from five animals. *,+P < 0.05 compared with sham and littermates exposed to CLP, respectively. (B) Survival rates. (C) Immunoblots of claudin-1, ZO-1 and occludin proteins in the small intestinal mucosa described in (A). The results in each panel were from one individual animal. (D) Quantitative analysis of the immunoblots as densitometry (n = 5).

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