Figure 3

Quantification of islet mass in pancreas sections. (A) Pancreas sections (8–10 sections per mouse) of 16-wk-old βarr2^+/+ and βarr2^−/− mice fed a chow diet or a HFD were stained with H&E. Representative micrographs of H&E staining of pancreatic sections from βarr2^+/+ and βarrZ^−/− mice. Scale bar: 500 µm. (B) Quantification of islet mass, (C) percentage islet area relative to pancreas, (D) islet density, (E) mean islet size and (F) islet size distribution of βarr2^+/+ and βarr2^−/− mice fed with a HFD (n = 3−5). *P < 0.05, **P < 0.01, versus βarr2^+/+ mice.