Figure 2

Low oxygen tension increases gene expression of EPOR but not of the β common receptor (βCR) in BAECs. Cells were cultured under 21% or 5% oxygen for 24 h, then EPOR (A) and βCR (B) expression was analyzed by quantitative PCR (qPCR). (C) VEGF, a known hypoxia-induced gene, was measured as a positive control. The data are expressed as arbitrary units versus the samples incubated in 21% oxygen and are expressed as the mean ± SEM of nine samples. *p < 0.05, p** < 0.01.