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Figure 3 | Molecular Medicine

Figure 3

From: BACE-1, PS-1 and sAPPβ Levels Are Increased in Plasma from Sporadic Inclusion Body Myositis Patients: Surrogate Biomarkers among Inflammatory Myopathies

Figure 3

BACE-1 (A), PS-1 (B) and sAPPβ (C) plasma levels in sIBM patients compared with healthy controls (HC), non-sIBM inflammatory myopathy patients (DM + PM) and non-sIBM patients (HC + DM + PM). HC, healthy controls; DM, dermatomyositis; PM, polymyositis. Increased levels of these amyloidogenic molecules in plasma from sIBM patients compared with healthy controls, DM and PM demonstrate their implication in sIBM disease and also strengthen their possible use for diagnostic purposes.

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