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Table 2 Logistic binary regression results in patients with sporadic inclusion body myositis (sIBM) compared with the remaining cohorts (healthy controls + DM + PM).

From: BACE-1, PS-1 and sAPPβ Levels Are Increased in Plasma from Sporadic Inclusion Body Myositis Patients: Surrogate Biomarkers among Inflammatory Myopathies

Molecule

Sensitivity (%)

Specificity (%)

Overall

AUC

Separately

    

BACE1

45.0

91.2

74.1

0.77 ± 0.07

PS1

38.1

82.4

65.5

0.62 ± 0.08

sAPPβ

11.1

97.0

66.7

0.68 ± 0.7

Combined

    

BACE1 + PS1 + sAPPβ

50.0

87.9

74.1

 

BACE1 + PS1

55.0

85.3

74.1

 

BACE1 + sAPPβ

44.4

87.9

72.5

 
  1. Logistic binary regression results in patients with sporadic inclusion body myositis (sIBM) compared with the remaining cohorts (healthy controls + DM + PM). The sensitivity and specificity of each molecule are shown separately and combined in addition to the AUC of each molecule.
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Molecular Medicine

ISSN: 1528-3658