Figure 3

(A) Immunoblots of SOD2 in the lung tumor (T) and nontumor (NT) of LC and LC-COPD patients. SOD2: superoxide dismutase 2; LC: lung cancer; COPD: chronic obstructive pulmonary disease; MW: molecular weights; KDa: kilodaltons. (B) Mean values and standard deviation (optical densities (OD) expressed in arbitrary units (a.u.)) of SOD2 protein content were significantly greater in the tumor lesions (T) compared with nontumor (NT) lungs in LC patients and LC-COPD as a group as well as in LC-COPD heavy smokers. The absence of any statistical sign means that no significant differences were found between groups for the different study comparisons. (C) I mmunoblots of SOD1 in the lung tumor (T) and nontumor (NT) of LC and LC-COPD patients. (D) Mean values and standard deviation (OD expressed in a.u.) of SOD1 protein content were significantly increased in both tumor (T) and nontumor (NT) lung specimens of LC-COPD patients compared with LC patients. The absence of any statistical sign means that no significant differences were found between groups for the different study comparisons. (E) Immunoblots of catalase in the lung tumor (T) and nontumor (NT) of LC and LC-COPD patients. (F) Mean values and standard deviation (OD expressed in a.u.) of catalase protein content was significantly reduced in the tumor lesions (T) compared with nontumor (NT) lungs in both LC-COPD and LC patients, as well as in LC-COPD heavy smokers. The absence of any statistical sign means that no significant differences were found between groups for the different study comparisons. SOD2, superoxide dismutase 2; MW, molecular weights; KDa, kilodaltons.