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Table 3 Identified carbonylated proteins in the lung specimens from the study patients.a

From: Redox Imbalance in Lung Cancer of Patients with Underlying Chronic Respiratory Conditions

Identified carbonylated protein

Accession no.

Mass

MASCOT score

Lung tumor lesions

   

α-Enolase, LC-COPD and LC

ENOA_HUMAN

47.48

163

Protein DJ-1, LC-COPD and LC

PARK7_HUMAN

19.9

384

α2-Macroglobulin, LC-COPD and LC

A2MG_HUMAN

163.2

99

Electron transfer flavoprotein subunit alpha, mitochondrial, LC-COPD

ETFA_HUMAN

35.1

490

Triosephosphate isomerase, LC-COPD

TPIS_HUMAN

26.7

418

Proteasome activator complex subunit 1, LC-COPD

PSME1_HUMAN

28.7

165

Thymidine phosphorylase, LC-COPD

TYPH_HUMAN

50.3

80

26S protease regulatory subunit 6A, LC-COPD

PRS6A_HUMAN

49.20

642

60 kDa heat shock protein, mitochondrial, LC-COPD

CH60_HUMAN

61.2

80

Actin, cytoplasmic 1, LC-COPD

ACTB_HUMAN

41.7

90

5′-AMP-activated protein kinase subunit γ-2, LC-COPD

AAKG2_HUMAN

63.2

63

Cofilin-1, LC

COF1_HUMAN

18.5

57

Transthyretin, LC

tthy_human

15.9

405

Ferritin light chain, LC

FRIL_HUMAN

20.06

92

Nontumor lung specimens

   

Protein DJ-1, LC-COPD and LC

PARK7_HUMAN

19.9

309

Transthyretin, LC-COPD and LC

tthy_human

15.9

68

Vimentin, LC-COPD and LC

VIME_HUMAN

53.6

172

Actin, cytoplasmic, LC-COPD and LC

ACTB_HUMAN

41.7

160

Serotransferrin, LC-COPD and LC

TRFE_HUMAN

79.29

169

Triosephosphate isomerase, LC-COPD and LC

TPIS_HUMAN

26.7

82

Serum amyloid P-component, LC-COPD and LC

SAMP_HUMAN

25.5

123

Glutathione S-transferase, LC-COPD and LC

GSTP1_HUMAN

23.6

80

ATP synthase subunit beta, LC-COPD and LC

ATPB_HUMAN

56.5

118

Carbonic anhydrase 1, LC-COPD and LC

CAH1_HUMAN

28.9

57

Apolipoprotein A-I, LC-COPD and LC

APOA1_HUMAN

30.8

83

Actin, cytoplasmic 1, LC-COPD and LC

ACTB_HUMAN

41.7

59

Hemoglobin subunit beta, LC-COPD and LC

HBB_HUMAN

16.0

62

  1. aDatabase: SwissProt 56.0. Protein scores greater than 56 are significant (p < 0.05).