Figure 3

Impaired contextual fear memory in CLP-exposed mice. (A) (Left) The graph shows the progression of freezing (mean ± SEM) during the training phase. Delivery of the tone CS (vertical light gray bars) coterminates with the foot-shock US (red lines). (Right) The box plot shows the freezing levels during the last 30 s of training, which are not significantly different (ns) between groups. (B) (Left) The graph shows freezing (mean ± SEM) during the tone memory test, in which the light gray bars indicate delivery of the tone CS. (Right) The box plot with the freezing levels during the tone presentations, which are similar between groups. (C) (Left) The graph shows freezing (mean ± SEM) during the context memory test. The gray bar indicates the 5–10 min interval during which the freezing response is calculated. (Right) The box plot shows significantly different freezing during the last 5 min (** P < 0.01 by t test).