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Figure 7 | Molecular Medicine

Figure 7

From: Preclinical Models of Overwhelming Sepsis Implicate the Neural System that Encodes Contextual Fear Memory

Figure 7

Unaltered basal dendrites in CA1 pyramidal neurons in CLP-exposed mice. (A) Traces of representative Golgi-stained CA1 neurons from the sham and CLP groups. (B) Micrographs show dendritic spines in CA1 basal dendrites. (C) The box plot of spine density in CA1 basal dendrites shows that spine counts are similar between groups; ns, nonsignificant by t test. (D) The table summarizes the data for CA1 pyramidal neurons from this study as well as previous data in references (10) and (47). The basal dendrites are similar between groups in terms of length and spine density, whereas the apical dendrites are disrupted in the CLP group.

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