Figure 4
From: Reduced Skin Blistering in Experimental Epidermolysis Bullosa Acquisita After Anti-TNF Treatment
TNF inhibition in antibody transfer-induced EBA was associated with changes in serum levels of IL-6, G-CSF and KC. Circulating IL-6, G-CSF and KC levels were evaluated in murine serum at d 12 of antibody transfer-induced EBA using Bio-Plex. Statistically significant reduction of all three molecules was observed in the serum of mice with blocked TNF function (TNF mAb/ETA, n = 6) compared with isotype-treated animals (n = 8; *p < 0.05, **p < 0.01).