Skip to main content
Figure 3 | Molecular Medicine

Figure 3

From: Genome-Wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A and Identification of ZBTB10 and Three Distinct HLA Associations

Figure 3

ZBTB10 association signals in LOMG (age of onset ≥50 years). The ordinate shows the strengths of the association signals, with the position on chromosome 8 shown in megabases (HG19 map) along the abscissa. The P value for each SNP is shown before (A) and after (B) conditioning with rs6998967, the strongest associated SNP, and rs1065238 (C), a SNP in strong LD, with probable regulatory effects (RegulomeDB score = 1f). The color-coded symbols correspond to the strength of linkage disequilibrium (based on HG19/1000 genome, November 2014, European population) with the most significantly associated SNP (purple filled circle) in each panel.

Back to article page

Molecular Medicine

ISSN: 1528-3658