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Figure 5 | Molecular Medicine

Figure 5

From: Genome-Wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A and Identification of ZBTB10 and Three Distinct HLA Associations

Figure 5

Analysis of the HLA region association signals in LOMG. In each panel, the symbols show the strength of the association signal (ordinate) for this region of chromosome 6 shown in Mb (HG19) along the abscissa; the SNPs, HLA antigens and HLA AAs are given color-coded symbols that correspond to the strength of LD with the most significantly associated SNP (purple filled circle). The P values for each variant are plotted: (A) no conditioning; (B) conditioning on HLA DQA1; (C) HLA DQA1 and HLA-A; and (D) HLA DQA1, HLA-A and class III SNP (rs2071596). Additional conditioning results are summarized in Table 4.

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Molecular Medicine

ISSN: 1528-3658