Table 3 Classic HLA associations in LOMG and comparison with EOMG.

HLA-A*01:01

0.13

0.15

1.09 × 10⁻¹

0.85 (0.70–1.04)

0.35

0.16

1.99 × 10⁻⁴⁴

2.99 (2.57–3.49)

HLA-A*03:01

0.20

0.15

9.20 × 10⁻⁵

1.42 (1.19–1.69)

0.08

0.14

5.92 × 10⁻⁹

0.56 (0.46–0.68)

HLA-C*07:01

0.11

0.15

1.80 × 10⁻⁴

0.67 (0.54–0.83)

0.52

0.34

5.67 × 10⁻³¹

2.18 (1.91–2.48)

HLA-C*05:01

0.05

0.08

1.88 × 10⁻³

0.64 (0.47–0.86)

0.03

0.10

7.84 × 10⁻¹³

0.44 (0.35–0.55)

HLA-B*07:02

0.18

0.15

1.20 × 10⁻²

1.26 (1.05–1.50)

0.07

0.14

3.54 × 10⁻¹¹

0.53 (0.44–0.64)

HLA-B*08:01

0.08

0.11

1.75 × 10⁻³

0.69 (0.54–0.88)

0.41

0.13

2.87 × 10⁻¹¹³

6.41 (5.46–7.53)

HLA-B*44:02

0.07

0.09

2.01 × 10⁻²

0.73 (0.56–0.96)

0.04

0.09

3.27 × 10⁻¹¹

0.44 (0.35–0.56)

HLA-DRB1*03:01

0.06

0.12

6.70 × 10⁻⁸

0.50 (0.39–0.66)

0.35

0.13

9.69 × 10⁻⁷⁴

4.70 (3.98–5.56)

HLA-DRB1*07:01

0.15

0.12

2.43 × 10⁻⁴

1.45 (1.19–1.76)

0.04

0.12

3.74 × 10⁻¹⁶

0.42 (0.34–0.52)

HLA-DRB1*13:01

0.03

0.07

1.90 × 10⁻⁷

0.39 (0.26–0.58)

0.04

0.06

3.18 × 10⁻⁰⁴

0.60 (0.46–0.79)

HLA-DRB1*15:01

0.18

0.14

3.10 × 10⁻³

1.31 (1.10–1.57)

0.10

0.14

8.92 × 10⁻⁰⁶

0.66 (0.55–0.79)

HLA-DQA1*05:01

0.15

0.24

5.92 × 10⁻¹²

0.54 (0.45–0.65)

0.43

0.24

3.63 × 10⁻⁴⁵

2.82 (2.44–3.26)

HLA-DQA1*02:01

0.15

0.12

2.96 × 10⁻⁴

1.44 (1.19–1.75)

0.04

0.12

3.19 × 10⁻¹⁶

0.42 (0.35–0.52)

HLA-DQA1*01:03

0.04

0.07

4.31 × 10⁻⁶

0.48 (0.34–0.68)

0.04

0.07

7.34 × 10⁻⁰⁴

0.64 (0.49–0.83)

HLA-DQB1*02

0.19

0.20

5.37 × 10⁻¹

0.95 (0.80–1.12)

0.37

0.22

1.63 × 10⁻³³

2.50 (2.16–2.90)

HLA-DQB1*02:01

0.06

0.12

1.23 × 10⁻⁷

0.52 (0.40–0.67)

NA

NA

NA

NA

HLA-DQB1*02:02

0.12

0.08

8.74 × 10⁻⁶

1.66 (1.33–2.06)

NA

NA

NA

NA