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Figure 6 | Molecular Medicine

Figure 6

From: Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions

Figure 6

Functional characterization of HLA-universal platelets (PLTs). PLTs derived from nontransduced iPSCs or iPSCs expressing a nonspecific shRNA (shNS) or a β2-microglobulin-specific shRNA (shβ2m) were stimulated with ADP and thrombin. The upregulation of CD62P (P-selectin) was analyzed. (A) Representative histogram of CD62P expression. (B) Graph displays mean and SD of the frequencies of CD62P as detected in three independent experiments. ***p ≤ 0.001, **p ≤ 0.01.

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Molecular Medicine

ISSN: 1528-3658