Figure 4

Enhanced neutrophil influx into the alveolar space of tlr9^−/− mice during S. aureus pneumonia. Wt (gray) and tlr9^−/− mice (white) were infected with 1 × 10⁷ MRSA bacteria via intranasal inoculation and euthanized at the indicated time points thereafter. (A) Neutrophils, (B) MIP-2 and (C) KC in BALF are expressed as box-and-whisker diagrams depicting the median, the smallest observation, lower quartile, median, upper quartile and largest observation (n = 8 mice per group at each time point). *p < 0.05, **p < 0.01 versus Wt mice at the same time point.