Figure 2

Effect of the combined treatment on the morphological structure of lung tissues in aged septic rats. Rats were sham operated or subjected to CLP with injection of vehicle (normal saline) or GG-2 (80 nmol/kg of ghrelin and 50 µg/kg of GH) at 5 h after CLP. The lung tissues were harvested at 20 h after CLP. Sections of lung tissues were stained with H&E and examined under light microscopy. (A) Representative images of the stained lung tissues are shown. Original magnification 200×. (B) Histologic injury scores of the lungs in different groups were quantified as described in Materials and Methods. Data are expressed as mean ± SE (n = 5–7 per group). *P < 0.05 versus sham and ^#P < 0.05 versus vehicle.