Figure 3From: Combined Administration of Human Ghrelin and Human Growth Hormone Attenuates Organ Injury and Improves Survival in Aged Septic RatsEffect of the combined treatment on lung inflammation in aged septic rats. Rats were sham operated or subjected to CLP with injection of vehicle (normal saline) or GG-2 (80 nmol/kg of ghrelin and 50 µg/kg of GH) at 5 h after CLP. The lung tissues were harvested at 20 h after CLP for measuring (A) protein levels of IL-6 by ELISA, mRNA l evels of (B) MIP-2 and (C) KC by qPCR, and (D) MPO activity by colorimetric assay. mRNA levels in sham group are designated 1 for comparison. Data are expressed as mean ± SE (n = 5–7 per group). *P < 0.05 versus sham and #P < 0.05 versus vehicle.Back to article page