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Table 2 Serum metabolic parameters measured under fed conditions on d 18 of pregnancy.

From: Peroxisome Proliferator-Activated Receptor γ 2 Modulates Late-Pregnancy Homeostatic Metabolic Adaptations

 

WT-C

WT-P

PPγ2KO-C

PPγ2KO-P

Glucose (mg/dL)

144.90 ± 5.21

126.9 ± 4.93†

145.50 ± 2.52

140.90 ± 6.78

Insulin (ng/mL)

0.43 ± 0.08

0.68 ± 0.20

0.48 ± 0.05

1.17 ± 0.22†#

Adiponectin (µg/mL)

5.67 ± 1.03

4.40 ± 0.34

2.50 ± 0.37§§

1.07 ± 0.08†##*

Leptin (ng/mL)

1.12 ± 0.17

6.40 ± 1.32††

1.60 ± 0.33

5.40 ± 0.89††##

Leptin/adiponectin

-

1.44

-

6.36

Glucagon (pg/mL)

117.80 ± 16.42

124.1 ± 44.99

215.0 ± 60.87

93.75 ± 40.04

FFA (mM)

-

0.43 ± 0.07

-

0.42 ± 0.05

Fasting FFA (mM)

-

0.67 ± 0.10

-

1.03 ± 0.37

TGs (mg/dL)

87.10 ± 11.94

117.80 ± 10.24

71.00 ± 4.89

144.41 ± 26.17†#

PAI-1 (ng/mL)

3.90 ± 0.98

39.20 ± 2.42†

1.90 ± 0.30§

47.40 ± 6.35†

IL-6 (pg/mL)

-

2.20 ± 0.23

-

2.60 ± 0.22

MCP-1 (pg/mL)

-

51.00 ± 7.02

-

49.90 ± 6.82

Progesterone (ng/mL)

-

1.20 ± 0.17

-

0.50 ± 0.15**

  1. Data are expressed as mean ± SEM (n = 6–10 animals/group). † p ≤ .05; †† p ≤ .01 pregnant versus non-pregnant, #p ≤ .05; ##p ≤ .01 PPγ2KO-P versus WT-C. §§p ≤ .01 PPγ2KO-C versus WT-C. *p ≤ .05; **p ≤ .01 PPγ2KO-P versus WT-P.