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Figure 1 | Molecular Medicine

Figure 1

From: N,N-Dimethylacetamide Significantly Attenuates LPS- and TNFα-Induced Proinflammatory Responses Via Inhibition of the Nuclear Factor Kappa B Pathway

Figure 1

DMA inhibits NO−2 secretion and iNOS expression. (A) NO−2 secretion was determined by Griess assay in LPS-stimulated RAW 264.7 cells after incubation with DMA and BAY 11-7082. (B) NO−2 secretion in LPS-stimulated RAW 264.7 cells after incubation with MMA. (C) Time profile of iNOS expression in LPS-stimulated RAW 264.7 cells. Data shown are means ± SEM of at least three independent experiments done in duplicate. * P ≤ 0.05; **** P≤ 0.0001. (D) Immunoblot analysis of iNOS expression after incubation with DMA and BAY 11-7082.

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Molecular Medicine

ISSN: 1528-3658