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Figure 4 | Molecular Medicine

Figure 4

From: N,N-Dimethylacetamide Significantly Attenuates LPS- and TNFα-Induced Proinflammatory Responses Via Inhibition of the Nuclear Factor Kappa B Pathway

Figure 4

DMA inhibits cytokine and chemokine secretion in LPS-stimulated human placental explants. ELISA was performed to determine levels of (A) TNFα, (B) IL-6, (C) IL-10, (D) IL-8 and (E) GM-CSF after incubation with DMA or SB 202190 in the presence of LPS after 20 h. Data shown are means ± SEM of experiments done in duplicate (n = 7). * P ≤ 0.05; ** P ≤ 0.01; *** P ≤ 0.001; **** P ≤ 0.0001.

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Molecular Medicine

ISSN: 1528-3658