Table 2 KEGG analysis of pathways regulated by miR-187.
KEGG pathway | Fold enrichment | Genes |
|---|---|---|
Pathways in cancer | +3.55 | HDAC2, JUN, KITLG, CDK6, APPL1, PTEN, FN, APC |
Chemokine signaling | −3.09 | CCL22, CXCL11, CCL5, STAT2, CXCL10 |
Cytokine-cytokine receptor interaction | −4.41 | CCL22, TNFSF10, IL22RA1, IL29, IFNB1, CXCL11, IL28B, CCL5, IL28A, CXCL10 |
Jak-STAT signaling | −4.47 | IL22RA1, IL29, 1FNB1, IL28A, IL28B, STAT2 |
Antigen processing and presentation | −5.57 | TAP1, HLA-B, CD74, HLA-F |
Toll-like receptor signaling | −6.87 | IFNB1, IRF7, TLR3, CXCL11, CCL5, CXCL10 |
Rig-1-like receptor signaling | −11.39 | DDX58, IFIH1, ISG15, IFNB1, IRF7, DHX58, CXCL10 |
Cytosolic DNA-sensing | −12.61 | DDX58, IFNB1, IRF7, CCL5, ZBP1, CXCL10 |