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Figure 1 | Molecular Medicine

Figure 1

From: The Effect of BAFF Inhibition on Autoreactive B-Cell Selection in Murine Systemic Lupus Erythematosus

Figure 1

Clinical outcomes of BAFF-R-Ig-treated 3H9 chimeric mice. (A, C) Male NZW/BXSB mice. (B, D) Female NZB/W mice. (A, B) ELISA values for each antigen were normalized to a high titer control run on each plate and are shown for each individual mouse at the indicated times after bone marrow transplant. The horizontal bar indicates the mean for each group (*p < 0.05). (C, D) Kaplan-Meier plots show significant delay in the onset of fixed 300 mg/dL proteinuria in BAFF-R-Ig-treated mice of both strains (*p < 0.05 versus untreated mice).

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Molecular Medicine

ISSN: 1528-3658