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Figure 4 | Molecular Medicine

Figure 4

From: The Effect of BAFF Inhibition on Autoreactive B-Cell Selection in Murine Systemic Lupus Erythematosus

Figure 4

The repertoire of Vκ light chains associated with the 3H9 heavy chain in follicular B-cell subsets from NZB/W (A) and NZW/BXSB (B) chimeras. The x axis shows the light-chain gene family and specific genes that were expressed. The y axis shows percent of the total repertoire for each subset. Four to six spleens were analyzed for each subset (see Supplementary Tables S2 and S3 for raw data and statistical analysis). Black dots indicate Vκ genes that confer specificity for dsDNA, histones or CL. Grey dots indicate Vκ genes without these specificities.

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