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Table 1 Histopathological change of pancreatic tissues in the mice model with acute pancreatitis induced by cerulein.

From: Spautin-1 Ameliorates Acute Pancreatitis via inhibiting impaired Autophagy and Alleviating Calcium Overload

Parameter

Group 1

Group 2

Group 3

P value*

Edema degree

1.00±0.00

3.25±0.5

2.25±0.5

<0.001/0.03

Inflammation degree

0.25±0.50

2.25±0.5

1.50±0.58

0.001/0.098

Vacuolization degree

0.00±0.00

2.75±0.96

2.00±0.00

0.001/0.168

Necrosis degree

0.00±0.00

1.25±0.50

0.50±0.58

0.002/0.098

Total score

1.25±0.50

9.50±1.29

6.25±1.26

<0.001/0.011

  1. *The P value indicates the statistical significance for the differences among Group 1 and 2/among Group 2 and 3.
  2. Group 1: saline control; Group 2: mice injected with cerulein; Group 3: mice injected with cerulein together with spautin-1.
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Molecular Medicine

ISSN: 1528-3658