Table 2 Relative mRNA levels of inflammasome components in PBMC normalized to ACTB/GAPDH/B2M. Data are derived from 62 male and 38 female patients.

AIM2

1.03 [0.14–9.42]

0.73 [0.04–1.72]

0.00009

NLRP3

1.59 [0.42–9.90]

0.58 [0.01–4.88]

0.000038

ASC (PYCARD)

2.89 [0.75–13.74]

1.24 [0.39–6.56]

0.000004

CASP1

1.06 [0.41–4.47]

0.67 [0.19–2.25]

0.000004

CASP5

1.22 [0.00–5.58]

0.18 [0.01–2.01]

< 0.000001

IL1B

2.34 [0.07–45.06]

0.25 [0.00–10.67]

< 0.000001