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Figure 4 | Molecular Medicine

Figure 4

From: Spare Adenosine A2a Receptors Are Associated with Positive Exercise Stress Test in Coronary Artery Disease

Figure 4

Identification of spare A2AR in patients with positive EST. (A) The dose-response curve resulting from Adonis binding to A2AR (KD; black circles; densitometry analysis of the 25 kDa band corresponding to the light chain of Adonis; see methods) and from dosage of the resulting cAMP production (EC50; white circles) for a representative patient with spare A2AR (EC50/KD ≤ 0.1) is shown. Results are mean ± SD of triplicates. (B) The corresponding Western blot analysis used for KD determination is shown.

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Molecular Medicine

ISSN: 1528-3658