Table 1 Cytokine concentrations in peritoneal fluid 6 h and 18 h after cecal slurry injection, without correction for total intraperitoneal fluid protein concentration.

6 h

Cytokine

Wild-Type pg/mL (IQR), n = 18

MMP8 null pg/mL (IQR), n = 21

P value

IL1β

148 (91–186)

242 (210–302)

< 0.001

IL6

14,874 (7273–16,782)

16,6692 (15),939–17,834)

0.038

IL10

955 (340–2030)

2,218 (1),417–3,188)

0.006

CCL3

572 (300–1,461)

1,441 (802–2,402)

0.038

LIX

911 (659–1,187)

1,001 (667–1,681)

0.291

TNFα

45 (26–70)

76 (62–92)

0.014

CXCL1

4,872 (1),321–15,078)

14,715 (6),206–16,474)

0.015

18 h

n = 20

n = 20

IL1β

137 (74–249)

288 (227–410)

0.020

IL6

2,256 (429–7,948)

20,285 (6),256–20,300)

0.032

IL10

1,031 (333–2,718)

1,967 (1),145–3,208)

0.306

CCL3

541 (324–1,230)

1,763 (1),102–3,203)

0.028

LIX

364 (114–517)

470 (396–687)

0.251

TNFα

73 (24–113)

112 (89–193)

0.067

CXCL1

1,064 (425–2,934)

8,910 (3),706–21,701)

0.012